Researchers are exploring how time-restricted feeding (TRF), a type of fasting, could help protect the brain against Alzheimer's disease.
In a study with mice that were genetically modified to develop Alzheimer's symptoms, scientists found that limiting their eating to just six hours a day helped improve their memory and reduced brain damage. This is important because Alzheimer's often disrupts the body's internal clock, leading to sleep problems, confusion and forgetfulness. By resetting this clock through fasting, the mice showed fewer signs of cognitive decline and had healthier brain activity.
What's particularly interesting is that the mice on a restricted diet had fewer harmful proteins called beta-amyloid plaques in their brains (the stuff that gets cleared out when you sleep) – which are linked to Alzheimer's. They also behaved more like healthy mice when it came to remembering where objects were placed in a maze.
While these findings are exciting, researchers emphasize that more studies are needed to see if TRF can have similar benefits for people. This research opens up new possibilities for non-drug approaches to slow down or even prevent Alzheimer's, making it a hopeful area for future exploration.
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