The concept of time has been described as many things: an arrow, a river, a march, anything that moves inextricably forward at a constant, unalterable rate. However, aging doesn't flow at such a uniform speed. Instead, humans age in fits and starts. A 2024 Stanford University study shows that our bodies age faster around our mid-40s and early 60s than during other stages of life. The study analyzed data from 108 people who donated blood and other biological samples over several years. By tracking 135,000 different molecules, creating 250 billion data points, scientists discovered that roughly 81% of the studied molecules showed age-related fluctuations, and those moments of rapid aging tended to coalesce around the ages of 44 and the early 60s. According to the scientists, the most surprising data point was rapid aging in the mid-40s. At first, they theorized that menopause or perimenopause could be playing a role in these changes, but they found the molecular changes impacted men just as much as women. The affected molecules also differed between those two aging periods. Both age groups reported changes in molecules related to cardiovascular disease, caffeine metabolism, and skin and muscle growth, but the mid-40s cohort also recorded increased alterations in alcohol metabolism, while people in their early 60s underwent changes to immune regulation and kidney function. Of course, a lifetime of healthy eating, exercise, and plentiful sleep can curtail some of the effects of these periods of aging, so it may be worth paying extra close attention to your health when those milestones arrive. |
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